ERCC2 iScience perspective paper

ERCC2 has published a perspective in iScience outlining our research goals.

Common Fund Data Ecosystem (CFDE) Virtual Workshop:

“Biomarker discovery from extracellular (cell-free) RNA-seq and tissue of origin from GTEx RNA-seq profiles”

Thursday September 12th 2024

1-3 pm ET / 10am-Noon PT

Requires Free Registration by September 9th (below)

Join us for an engaging hands-on workshop where Srimeenakshi (Meenu) Srinivasan of the Louise Laurent Lab at the University of California-San Diego will demonstrate how to perform integrative data analysis utilizing data from two Common Fund Data Ecosystem (CFDE) Data Coordinating Center portals followed by an interactive Q&A session.

The featured use case will illustrate biomarker discovery from extracellular cell-free RNA-seq data with tissue of origin identification through integrative analysis of GTEx tissue-derived RNA-seq data and plasma-derived small RNA-seq data from the ERCC exRNA Atlas.

To conduct workshop exercises in real time, attendees wishing to take part in the hands-on analysis will need to have the following installed prior to dialing into the workshop as there will not be time to conduct installations during the workshop.

  • Python (3.10 or greater)
  • R (4.2 or greater)
  • R packages (latest versions): 
    • data.table
    • tidyr
    • reshape2
    • dplyr
    • gdata DESeq2
    • BiocParallel
    • ggplot2
    • ggsignif

We also strongly encourage attendees to have Jupyter Notebook installed as well as this will be the platform used during the workshop. The Jupyter Notebook/files that will be used will be sent out via email.

Attendees who are not looking to conduct the analyses during the workshop are welcome to attend and observe.

A link to the virtual meeting will be provided in a confirmation email.

If you have any questions, please feel free to contact us at info@exrna.org

We look forward to seeing you there!

 

REGISTER HERE

 

To learn more about the projects & resources that will be discussed please see:

Common Fund Data Ecosystem (CFDE): https://commonfund.nih.gov/dataecosystem

Extracellular RNA Communication Consortium (ERCC):  https://exrna.org/

Genotype-Tissue Expression Project (GTEx): https://www.gtexportal.org/

Registration and more information: 

ASIC Annual Meeting

When: October 17 – 19, 2024
Where: Bethesda North Marriott Hotel & Conference Center

Abstracts are due August 30, 2024
Registration deadline: September 25, 2024

The ASIC Annual Meeting is an intellectual “home” and support network for new and seasoned investigators, students, and postdocs. Over three days you’ll exchange ideas on emerging questions and cutting-edge developments in non-EV research including:

Extracellular Vesicles (EVs)
Extracellular Particles (EPs)
Particulate carriers of extracellular RNA (exRNA) as biological mediators, regulators, and diagnostic analytes.

The meeting also covers a broad range of intercellular communication processes including:

EVs
EPs
exRNA in Cancer
CNS Diseases
Infections (both bacterial and viral)

WHY ATTEND?
You’ll have a valuable opportunity to network with investigators from diverse scientific and clinical fields, discuss and advance the impact of EV/EP/ExRNA in diagnostics and treatments, and better understand the biogenesis of normal vs. disease states.

Are you new to the field? You can work with colleagues and mentors so you can improve your grants and develop their skills to become successful independent researchers.

Women and those from underrepresented groups are especially encouraged to attend and connect with seasoned researchers who have years of mentoring experience.

Keep up with developments in the field of exRNA research!

Sign up for periodic updates from the ERCC, including announcements about our monthly webinar series.